The Prime Minister's Office said it offered the condolences of the Israeli people to Egyptian President Abdel Fattah al-Sisi and the Egyptian people and "sends its good wishes to the injured."
Israel also called for united forces with other countries "to defeat terrorism more quickly."
"There is no difference between terrorism that inflicts Egypt and terrorism that inflicts other countries," the statement said.
At least 16 Egyptian policemen were killed Friday in fire exchanges with terrorists in Giza province, Egypt's Interior Ministry said.
Egypt has been fighting against a wave of terror activities that killed hundreds of policemen and soldiers since the military toppled former Islamist president Mohamed Morsi in July 2013 in response to mass protests against his one-year rule and his currently outlawed Muslim Brotherhood group.
Terror attacks in Egypt used to be centered in North Sinai before spreading nationwide and killing hundreds of policemen and soldiers over the past few years.