Iran's Supreme Leader Ayatollah Ali Khamenei speaks in Mashhad, 924 km east of Tehran, on May 15, 2007. (Reuters File photo)

TEHRAN, Feb. 13 (Xinhua) -- Iran's supreme leader on Wednesday ruled out the possibility of negotiations with the United States over the existing issues.

"As for America, no solution for the (existing mutual) problems is in prospect," Ayatollah Ali Khamenei said in a statement published by his official website.

"Talks with America will bear no fruit, but material and spiritual loss for the Islamic republic," Khamenei was quoted as saying.

"Today, the Iranian nation considers the criminal America, as well as some European states, as deceptive and untrustworthy," he said.

Khamenei had earlier said that the Islamic republic would not hold new negotiations with the "cheating" United States referring to the U.S. withdrawal from the Iranian international nuclear deal, known also as the Joint Comprehensive Plan of Action (JCPOA).

U.S. President Donald Trump decided to quit the 2015 nuclear pact in May 2018, reimposed tough sanctions lifted under the accord against Iran and vowed to inflict punishments like secondary sanctions on nations that have business links with Iran.

Washington's withdrawal from the landmark nuclear deal was criticized across the world.