TOKYO, Oct. 14 (Xinhua) -- Tokyo stocks closed mixed Wednesday following Wall Street's weak lead overnight, as investor sentiment was dented as a stalemate in U.S. fiscal stimulus negotiations continued and drugmakers pausing COVID-19 vaccine trials and antibody treatments caused concern.
The 225-issue Nikkei Stock Average added 24.95 points, or 0.11 percent, from Tuesday to close the day at 23,626.73.
The broader Topix index of all First Section issues on the Tokyo Stock Exchange, meanwhile, lost 5.20 points, or 0.32 percent, to finish at 1,643.90.
Retail and precision instrument issues led notable gainers, while air transportation, and iron and steel issues comprised those that declined the most. Enditem