China to launch clinical trial of long-lasting HIV vaccine: paper

新华网| 2019-07-19 16:50:21|Editor: 华夏
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Photo taken on Nov. 30, 2017 shows 293T cell for the AIDS vaccine research at the National Engineering Laboratory for AIDS Vaccine at Jilin University in Changchun, northeast China's Jilin Province. (Xinhua/Xu Chang)

BEIJING, July 19 (Xinhua) -- Chinese scientists will begin the second-phase clinical trial of an HIV vaccine on 160 volunteers, Friday's China Daily reported.

The candidate vaccine, DNA-rTV, relies on replication of the DNA of HIV to stimulate effective immunization, according to Shao Yiming, a chief HIV researcher at the Chinese Center for Disease Control and Prevention, adding that it's the first such HIV vaccine to begin a second-phase clinical trial.

This vaccine under development, which contains DNA segments from HIV instead of the full human immunodeficiency virus, will have a stronger and longer-lasting effect. It is also designed to target the HIV strains that are most common in China, Shao was cited by the newspaper as saying.

More than 130 volunteers have been recruited so far, and the initial work is underway at a hospital in Beijing and another in the city of Hangzhou, he added.

"Hopefully the second-phase trial will be completed in the latter half of 2021, and the third-phase clinical trial may start at the end of that year, which will involve thousands of volunteers in a trial to test the effectiveness of the vaccine to protect people against HIV," Shao said. Enditem

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